BDBM50003127 CHEMBL122193::CHEMBL1626562::CHEMBL16659::choline salt of 5-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-3H-[1,3,4]thiadiazole-2-thione

SMILES CC(C)(C)c1cc(cc(c1O)C(C)(C)C)-c1nnc(S)s1

InChI Key InChIKey=MYNMGQGXYYHMEX-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50003127   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003127(CHEMBL122193 | CHEMBL1626562 | CHEMBL16659 | choli...)
Affinity DataIC50:  2.80E+3nMAssay Description:The compound was tested for the inhibition of 5-lipoxygenase in intactbasophilic rat leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003127(CHEMBL122193 | CHEMBL1626562 | CHEMBL16659 | choli...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of 5-lipoxygenase measured by the reduction of leukotriene B4 (LTB4) in intact basophilic rat leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003127(CHEMBL122193 | CHEMBL1626562 | CHEMBL16659 | choli...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibitory activity against 5-LipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50003127(CHEMBL122193 | CHEMBL1626562 | CHEMBL16659 | choli...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of 5-LO (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed